Author Archives: Shula

Science Library Text Collection – updated

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Today I have finally listed all the “open” research studies collected up to now.  This brings the Library Text Collection up to more than 3,000 papers listed. Now to start the next part of the project — updating the list … Continue reading

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Rainbow-colored cake anybody?

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In study after study, the dangers of artificial food dyes are documented.  Nevertheless, many of us would still like to provide colorful party foods for our families.  What to do?  Of course, bright fruits such as blueberries and strawberries can … Continue reading

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Feingold 1978: Address to California School Food Service Association, Sacramento, CA

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Although this speech was given in 1978, it could equally apply today.  Tragically, his warning went unheeded, and nothing has changed. Ladies and Gentlemen: I am pleased to be with you today to discuss the importance of the School Food … Continue reading

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Choudhary 2017: Neurophysiological symptoms and aspartame: What is the connection?

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Nutritional Neuroscience, 2017 Feb 15:1-11. This is a review of studies linking neuro-physiological symptoms to aspartame usage which concludes that aspartame may be responsible for adverse neurobehavioral health outcomes. QUOTE:  “Aspartame consumption needs to be approached with caution due to … Continue reading

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Soffer 2016: A case of chronic contact dermatitis resulting from the use of blue hair dye

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Contact Dermatitis. 2016 Oct;75(4): 258-9 This is a case report about a 45-year-old woman who began to dye her hair blue.  After several years of rashes and itching on her scalp, face, and neck, she sought help from an allergist.  … Continue reading

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Mawson 2017: Pilot comparative study on the health of vaccinated and unvaccinated 6- to 12-year-old U.S. children

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Journal of Translational Science, Volume 3(3): 1-12.  doi: 10.15761/JTS.1000186 This is one of the first studies done to address the questions raised by the U.S. Institute of Medicine about the long term health outcomes of the vaccination schedule as used … Continue reading

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Senate Health Committee approves Wieckowski bill to study dangers of synthetic food dyes on children

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SB 504 calls for state office to conduct independent review of evidence and options for the Legislature April 26, 2017 The Senate Health Committee today approved a bill by Senator Bob Wieckowski (D-Fremont) to direct a state agency to review … Continue reading

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Khayyat 2017: Tartrazine induces structural and functional aberrations and genotoxic effects in vivo

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PeerJ. 2017 Feb 23;5: e3041. This study was done to evaluate the possible adverse effects of the color Tartrazine (Yellow 5) on kidney and liver function and structure in rats, as well as its affect on white blood cells.  For … Continue reading

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Feitosa 2017: Estimate of the theoretical maximum daily intake of Sunset Yellow FCF by the Brazilian population

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Food Additives & Contaminants Part A. 2017 Feb 20:1-8 This study was  able to estimate daily intake of foods containing Sunset Yellow (Yellow 6) using the 2008-2009 data collections of food purchases by the Brazilian Institute of Geography and Statistics.  … Continue reading

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Bastaki 2017: Estimated Daily Intake and Safety of FD&C Food Colour Additives in the US Population

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Food Additives & Contaminants, Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment. 2017 March 23. Using complex statistics and a database of product  labels, rather than direct measurements, an  “estimate of daily intake” of the amounts of synthetic food … Continue reading

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Pestana 2010: Safety of ingestion of yellow tartrazine by double-blind placebo contgrolled challenge in 26 atopic adults.

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Allergologie et Immunopathologia (Madrid). 2010 May-June; 38 (3): 142-6. In this study, styling itself as a “gold standard, double-blind placebo controlled, crossed-over challenge,” 26 adults with atopy (skin or asthma allergy) were tested for tartrazine (Yellow 5) sensitivity and had … Continue reading

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Book: Waging War on the Autistic Child

The Arizona 5 and the Legacy of Baron von Münchausen, by Andrew J. Wakefield (2012) PROLOGUE “What is the loss of job, career, professional license, honors, colleagues, and country against that of a child’s voice? How do the very public … Continue reading

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Newson 2003: Pathological demand avoidance syndrome: A necessary distinction within the pervasive developmental disorders.

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Archives of Disease in Childhood. 2003 July; 88(7): 595-600. Newson here proposes that PDA should be considered a separate entity within the pervasive developmental disorders. Table 1 on Page 597 gives a detailed description of such a child, using 8 … Continue reading

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O’Nions 2014: Pathological demand avoidance: Exploring the behavioural profile

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Autism. 2014,  July; 18(5): 538-44. This is the first report comparing the profiles of children labelled PDA to those in  other groups with behavioral overlap. For example, children with conduct problems are strongly motivated by rewards; for PDA, however, rewards … Continue reading

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Reilly 2014: Pathological Demand Avoidance in a population-based cohort of children with epilepsy: Four case studies

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Research in Developmental Disabilities. 2014 Dec; 35(12): 3236-44 Children with epilepsy often have other neurological problems such as autism and ADHD.  This paper is a detailed report on four children with epilepsy as ell as symptoms of PDA (Pathological Demand … Continue reading

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Gillberg 2014: Commentary: PDA – public display of affection or pathological demand avoidance? – reflections on O’Nions et al. (2014)

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Journal of Child Psychology and Psychiatry. 2014 July; 55(7):769-70 Beginning with a comment on “PDA” as sometimes used to mean “Public Display of Affection,” Gillberg says that in his own 40 years of clinical experience, PDA/EDA is not at all … Continue reading

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Gillberg 2015: Extreme (“pathological”) demand avoidance in autism: a general population study in the Faroe Islands

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European Child & Adolescent Psychiatry. 2015. August; 24(8): 979-84. The Faroe Islands are a cluster of 18 rocky, volcanic islands which form a self-governing archipelago, part of the Kingdom of Denmark.  They are located in the open seas betwen the … Continue reading

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O’Nions 2014: Development of the ‘Extreme Demand Avoidance Questionnaire’ (EDA-Q): preliminary observations on a trait measure for Pathological Demand Avoidance.

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Journal of Child Psychology and Psychiatry 55:7 (2014), pp 758–768 This paper is about the development and validation of the ‘Extreme Demand Avoidance Questionnaire’  (EDA-Q), to aid in diagnosis of PDA (Pathological Demand Avoidance) traits. PDA (or EDA) is a … Continue reading

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O’Nions 2016: Identifying features of ‘pathological demand avoidance’ using the Diagnostic Interview for Social and Communication Disorders (DISCO)

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European Child & Adolescent Psychiatry. 2016 April; 25(4): 407-19 The term “pathological demand avoidance” (PDA) describes children or adults within the autism spectrum who exhibit obsessive resistance to everyday demands and requests.  In this study, the authors determined specific differences … Continue reading

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Rafati 2017: Using vitamin E to prevent the impairment in behavioral test, cell loss and dendrite changes in medial prefrontal cortex induced by tartrazine in rats

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Acta Histochemica. 2017 March; 119(2): 172-180 The authors used a rat model to answer the following questions: Does exposure to tartrazine (Yellow 5)  influence the rats’ memory and learning? Does the tartrazine exposure have any effects on the volume of … Continue reading

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Hutcheon 2016: Detectable Risks in Studies of the Fetal Benefits of Maternal Influenza Vaccination

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American Journal of Epidemiology, 2016 Aug 1; 184(3):227-32 Giving pregnant women the flu shot is expected not only to prevent the flu in both mothers and newborns, but also to prevent adverse pregnancy outcomes such as preterm birth.  According to … Continue reading

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Ly 2017: Elimination diets’ efficacy and mechanisms in attention deficit hyperactivity disorder and autism spectrum disorder.

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European Child & Adolescent Psychiatry.  2017.  Feb 11.    doi: 10.1007/s00787-017-0959-1 In her review of the research, Dr. Ly discusses the use of elimination diets for ADHD and autism from the point of view of the interaction of the metabolic, immune, … Continue reading

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Ríos-Hernández 2017: The Mediterranean Diet and ADHD in Children and Adolescents

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Pediatrics,  2017 Jan 30. pii: e20162027 This study took place in Spain, where families have a long tradition of eating the Mediterranean diet.  As diets today veer away from traditional healthful foods towards junk food, candies and convenience foods, behavior … Continue reading

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Silent Epidemic; The Untold Story of Vaccines

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This Gary Null Production is a long film – almost 2 hours – so get comfortable before you start.   Although some parents are quoted in this film, most of the participants are medical doctors and researchers. Please share this film … Continue reading

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Malin 2015: Exposure to fluoridated water and attention deficit hyperactivity disorder prevalence among children and adolescents in the United States: an ecological association

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Environmental Health, Feb 27;14:17. doi: 10.1186/s12940-015-0003-1. The authors comment that while environmental factors known to increase the risk of ADHD include exposure to manganese, poly-chlorinated biphenyls (PCBs), nicotine, mercury, arsenic, food additives, food coloring, pesticides and lead, almost no attention … Continue reading

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Bataineh 2006: Impact of 12-week ingestion of sodium fluoride on aggression, sexual behavior, and fertility in adult male rats

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Fluoride, 39 (4), 293-301. Giving adult male rats 100 ppm and 300 ppm (parts per million) of sodium fluoride in their drinking water for 12 weeks resulted in less testosterone, fewer (and weaker) sperm, less aggressive behavior, and less successful … Continue reading

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Hormann 2014: Holding Thermal Receipt Paper and Eating Food after Using Hand Sanitizer Results in High Serum Bioactive and Urine Total Levels of Bisphenol A (BPA)

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PLoS One. 2014 Oct 22;9(10): e110509. If you must handle thermal receipts, don’t use sanitizers or hand lotion – both often contain chemicals that will encourage the BPA to slide right through your skin. In the experiment described in this … Continue reading

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Lioutas 2015: “I saw Santa drinking soda!” Advertising and children’s food preferences

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Child Care Health & Development. 2015 May;41 (3):424-33 This study examines the “mechanisms by which food advertising prompts children’s consumer behavior.” The children respond to advertising by (1) an increase in expectations and purchase motivation, (2) happiness upon acquiring the … Continue reading

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Saunders 2016: Reconsidering dietary polyunsaturated fatty acids in bipolar disorder: A translational picture

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The Journal of Clinical Psychiatry. 2016 Oct;77(10): e1342-e1347 Drugs used for bipolar disorder often work by down-regulating the brain metabolism of a long-chain omega-6 (or n-6) essential fatty acid called arichidonic acid (AA).  The shorter-chain omega-6 (or n-6) essential fatty … Continue reading

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Sommer 2015: Treatment of aspirin exacerbated respiratory disease with a low salicylate diet: a pilot crossover study.

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Otolaryngology Head & Neck Surgery. 2015 Jan; 152(1): 42-47. Aspirin exacerbated respiratory disease (AERD) is comprised of aspirin/acetyl-salicylic acid (ASA) sensitivity, bronchial asthma, and nasal polyposis.  Treatment may include steroids, surgery, and/or aspirin desensitization. In this study of 10 patients, … Continue reading

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Sommer 2016: A novel treatment adjunct for aspirin exacerbated respiratory disease: the low-salicylate diet: a multicenter randomized control crossover trial

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International Forum of Allergy & Rhinology. 2016. April; 6(4): 385-91 30 patients diagnosed with aspirin sensitivity and aspirin-exacerbated respiratory disease (AERD) were entered into a diet trial.   They ate either a regular diet or a low-salicylate diet for 6 … Continue reading

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Schapowal 1995: Phenomenology, pathogenesis, diagnosis and treatment of aspirin-sensitive rhinosinusitis.

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Acta Otorhinolaryngologica Belgica. 1995;49(3): 235-50. In this review of aspirin-sensitive rhinosinusitis, it is described as a non-allergic, non-infectious perennial eosinophilic rhinitis starting in middle age and rarely seen in children. It may also been seen in atopic patients who have … Continue reading

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Zou 2011: Tourette syndrome and excitatory substances: Is there a connection?

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Childs Nervous System. 2011 May;27(5): 793-802 This is one of the first studies to investigate the relationship between dietary components and Tourette syndrome (TS). Using the laboratory that tested the Olympic Games  contestants for illegal stimulant drugs, the researchers tested … Continue reading

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Sasaki 2002: The comet assay with 8 mouse organs: Results with 39 currently used food additives

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Mutation Research. 2002 Aug 26; 519(1-2): 103-19. Sasaki et al, in Japan, tested 39 common food additives — dyes, color fixatives, preservatives, antioxidants, fungicides, and sweeteners.   They gave each additive separately by mouth to groups of four male mice, and … Continue reading

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Ghanizadeh 2015: The effect of dietary education on ADHD, a randomized controlled clinical trial

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Annals of General Psychiatry (2015) March 1; 14:12 This was a study on children with ADHD who were already receiving Ritalin therapy, to see if improving their diet in general might make a difference.  The children were divided into two … Continue reading

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Dixit 2013: All India survey for analyses of colors in sweets and savories: Exposure risk in Indian population

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Journal of Food Science. 2013 April; 78(4): T642-7 This is the first national study on food additive use in India, collecting data on “sweets and savories.” Their dye extraction and identification technique (using pure wool strands) is described, as is … Continue reading

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Arnold 1999: Treatment alternatives for Attention-Deficit/ Hyperactivity Disorder (ADHD)

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Journal of Attention Disorders, Vol. 3(1): 30-48 (1999) This review of “alternative” treatments was undertaken for the National Institute of Health (NIH) 1998 Consensus Development Conference on ADHD.  23 such treatments were identified.  Some were considered effective or possibly effective … Continue reading

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Nigg 2012: Meta-Analysis of Attention-Deficit/Hyperactivity Disorder or Attention-Deficit/Hyperactivity Disorder Symptoms, Restriction Diet, and Synthetic Food Color Additives

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Journal of the American Academy of Child and Adolescent Psychiatry. 2012 Jan; 51(1): 86–97.e8. This meta-analysis of 24 published studies on food colors, plus 10 more on dietary restriction, concluded that a restriction diet (e.g., the Feingold diet or an … Continue reading

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Cormier 2007: Diet and child behavior problems: Fact or fiction?

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Pediatric Nursing. 2007 Mar-Apr; 33(2): 138-43. This review is intended to help nurses support parents who want to try various therapeutic diets such as the Feingold diet, oligoantigenic (few foods) diet, or gluten-free, casein-free diet for their children.  The nurses … Continue reading

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Breakey 1997: The role of diet and behaviour in childhood

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Journal of Paediatrics and Child Health. 1997 June; 33(3): 190-4. The author summarizes and discusses the research from the 1970s up until the 1990s.  She emphasizes that studies often only can deal with a single item but in actuality there … Continue reading

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