Category Archives: Food Dyes

Rainbow-colored cake anybody?

This gallery contains 3 photos.

In study after study, the dangers of artificial food dyes are documented.  Nevertheless, many of us would still like to provide colorful party foods for our families.  What to do?  Of course, bright fruits such as blueberries and strawberries can … Continue reading

More Galleries | Leave a comment

Soffer 2016: A case of chronic contact dermatitis resulting from the use of blue hair dye

This gallery contains 2 photos.

Contact Dermatitis. 2016 Oct;75(4): 258-9 This is a case report about a 45-year-old woman who began to dye her hair blue.  After several years of rashes and itching on her scalp, face, and neck, she sought help from an allergist.  … Continue reading

More Galleries | Leave a comment

Senate Health Committee approves Wieckowski bill to study dangers of synthetic food dyes on children

This gallery contains 2 photos.

SB 504 calls for state office to conduct independent review of evidence and options for the Legislature April 26, 2017 The Senate Health Committee today approved a bill by Senator Bob Wieckowski (D-Fremont) to direct a state agency to review … Continue reading

More Galleries | 2 Comments

Khayyat 2017: Tartrazine induces structural and functional aberrations and genotoxic effects in vivo

This gallery contains 3 photos.

PeerJ. 2017 Feb 23;5: e3041. This study was done to evaluate the possible adverse effects of the color Tartrazine (Yellow 5) on kidney and liver function and structure in rats, as well as its affect on white blood cells.  For … Continue reading

More Galleries | Leave a comment

Feitosa 2017: Estimate of the theoretical maximum daily intake of Sunset Yellow FCF by the Brazilian population

This gallery contains 1 photo.

Food Additives & Contaminants Part A. 2017 Feb 20:1-8 This study was  able to estimate daily intake of foods containing Sunset Yellow (Yellow 6) using the 2008-2009 data collections of food purchases by the Brazilian Institute of Geography and Statistics.  … Continue reading

More Galleries | Leave a comment

Bastaki 2017: Estimated Daily Intake and Safety of FD&C Food Colour Additives in the US Population

This gallery contains 2 photos.

Food Additives & Contaminants, Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment. 2017 March 23. Using complex statistics and a database of product  labels, rather than direct measurements, an  “estimate of daily intake” of the amounts of synthetic food … Continue reading

More Galleries | Leave a comment

Pestana 2010: Safety of ingestion of yellow tartrazine by double-blind placebo contgrolled challenge in 26 atopic adults.

This gallery contains 2 photos.

Allergologie et Immunopathologia (Madrid). 2010 May-June; 38 (3): 142-6. In this study, styling itself as a “gold standard, double-blind placebo controlled, crossed-over challenge,” 26 adults with atopy (skin or asthma allergy) were tested for tartrazine (Yellow 5) sensitivity and had … Continue reading

More Galleries | Leave a comment

Rafati 2017: Using vitamin E to prevent the impairment in behavioral test, cell loss and dendrite changes in medial prefrontal cortex induced by tartrazine in rats

This gallery contains 2 photos.

Acta Histochemica. 2017 March; 119(2): 172-180 The authors used a rat model to answer the following questions: Does exposure to tartrazine (Yellow 5)  influence the rats’ memory and learning? Does the tartrazine exposure have any effects on the volume of … Continue reading

More Galleries | Leave a comment

Sasaki 2002: The comet assay with 8 mouse organs: Results with 39 currently used food additives

This gallery contains 3 photos.

Mutation Research. 2002 Aug 26; 519(1-2): 103-19. Sasaki et al, in Japan, tested 39 common food additives — dyes, color fixatives, preservatives, antioxidants, fungicides, and sweeteners.   They gave each additive separately by mouth to groups of four male mice, and … Continue reading

More Galleries | Leave a comment

Dixit 2013: All India survey for analyses of colors in sweets and savories: Exposure risk in Indian population

This gallery contains 2 photos.

Journal of Food Science. 2013 April; 78(4): T642-7 This is the first national study on food additive use in India, collecting data on “sweets and savories.” Their dye extraction and identification technique (using pure wool strands) is described, as is … Continue reading

More Galleries | Leave a comment

Breakey 1997: The role of diet and behaviour in childhood

This gallery contains 1 photo.

Journal of Paediatrics and Child Health. 1997 June; 33(3): 190-4. The author summarizes and discusses the research from the 1970s up until the 1990s.  She emphasizes that studies often only can deal with a single item but in actuality there … Continue reading

More Galleries | Leave a comment

Schnoll 2003: Nutrition in the treatment of Attention-Deficit Hyperactivity Disorder: A neglected but important aspect

This gallery contains 2 photos.

Applied Psychophysiology and Biofeedback, 2003 March; 28(1): 63-75. In this paper, Schnoll reviews the research on food additives, refined sugars, food allergies, and fatty acid metabolism as it relates to ADHD. QUOTE:  “Although clinicians and researchers alike acknowledge the complex … Continue reading

More Galleries | Leave a comment

Konikowska 2012: The influence of components of diet on the symptoms of ADHD in children

This gallery contains 2 photos.

Roczniki Panstwowego Zakladu Higieny. 2012;63(2): 127-34 In this review of ADHD treatments, Konikowska describes hyperactivity as a genetic trait connected to abnormal brain maturation, likely related to less activity by neurotransmitters dopamine and norepinephrine.  While stimulant medications effectively increase the … Continue reading

More Galleries | Leave a comment

Umezawa 2012: Effect of fetal exposure to titanium dioxide nanoparticle on brain development – brain region information

This gallery contains 2 photos.

The Journal of Toxicological Sciences, Vol. 37, No. 6, 1247-1252. 2012 By studying the brains of mice whose mothers were exposed to titanium dioxide (TiO2) nanoparticles during pregnancy, the researchers determined changes in gene expression affecting several parts of the … Continue reading

More Galleries | Leave a comment

Kubo-Irie 2016: The transfer of titanium dioxide nanoparticles from the host plant to butterfly larvae through a food chain

This gallery contains 3 photos.

Scientific Reports, 2016 March 31;6:23819 The purpose of this study was to better  understand how the widely used titanium dioxide may impact the environment.  The researchers used swallowtail butterfly larvae which were hatched on plants growing in water containing titanium … Continue reading

More Galleries | Leave a comment

Mansouri 2016: Histopathological effects following short-term coexposure of Cyprinus carpio to nanoparticles of TiO2 and CuO

This gallery contains 2 photos.

Environmental Monitoring and Assessment. (2016) 188:575 This Swiss study looks at the effect of two kinds of nanoparticles, separately and combined.  Both copper oxide (CuO) and titanium dioxide (TiO2) ultrafine particles (nanoparticles or NP) are widely used in many things … Continue reading

More Galleries | Leave a comment

Jovanovic 2016: Food web effects of titanium dioxide nanoparticles in an outdoor freshwater mesocosm experiment.

This gallery contains 2 photos.

Nanotoxicology. 2016 Sep;10(7):902-12. In this study, 25 µg/L and 250 µg/L of the food color additive titanium dioxide (TiO2) nanoparticles were added to outdoor mesocosms* placed in a lake.  The control mesocosm was not treated with any TiO2. * A … Continue reading

More Galleries | Leave a comment

Ze 2014: Neurotoxicity and gene-expressed profile in brain-injured mice caused by exposure to titanium dioxide nanoparticles

This gallery contains 3 photos.

Journal of Biomedical Materials Research Part A. 2014 Feb; 102(2): 470-8. Titanium dioxide is a naturally occurring white powder approved by the FDA.  It is used as a white coloring in many products we use every day such as toothpaste, … Continue reading

More Galleries | Leave a comment

El-Wahab 2013: Toxic effects of some synthetic food colorants and/or flavor additives on male rats

This gallery contains 1 photo.

Toxicology and Industrial Health, 2013.  March; 29(2): 224-32.  doi: 10.1177/0748233711433935 The researchers wanted to evaluate the toxic effect of some synthetic colorants and/or flavors on body organs and metabolism in rats.   They used 10 groups of 10 male albino rats … Continue reading

More Galleries | Leave a comment

Wuthrich 1981: Acetylsalicylic acid and food additive intolerance in urticaria, bronchial asthma and rhinopathy

This gallery contains 2 photos.

Schweizerische medizinische Wochenschrift (Swiss medical weekly), 1981. Sep 26; 111(39): 1445-50 Wuthrich wrote that adverse reactions to aspirin, additives such as tartrazine (Yellow 5) and the preservative benzoate are seen all over the world.  It is described as an intolerance … Continue reading

More Galleries | Leave a comment

Spector 1979: Aspirin and concomitant idiosyncrasies in adult asthmatic patients

This gallery contains 1 photo.

Journal of Allergy & Clinical Immunology, 1979 Dec;64(6 Pt 1):500-6 In this study, a positive response was defined as a 20% fall in forced expiratory volume in 1 second  (FEV1) for up to 4 hours.  The researchers tested several hundred … Continue reading

More Galleries | Leave a comment

Ishihara 1979: Experimental investigation on the pathogenesis of tartrazine-induced asthma

This gallery contains 2 photos.

Tohoku Journal of Experimental Medicine, 1979. Nov; 129(3): 303-9. In this study on guinea pigs, the researchers showed that the dye Yellow 5 potentiates asthmatic reactions to other broncho-constrictors. In other words, the dye may not cause an asthma attack … Continue reading

More Galleries | Leave a comment

Goldenring 1980: Effects of continuous gastric infusion of food dyes on developing rat pups.

This gallery contains 2 photos.

Life Sciences. 1980 Nov 17;27(20):1897-904. In this study, some rats were treated with 6-OHDA and some were treated with placebo.  In each of these groups, some were given food dyes and some were given placebo, resulting in 4 groups of … Continue reading

More Galleries | Leave a comment

Saxena 2015: Food Color Induced Hepatotoxicity in Swiss Albino Rats, Rattus norvegicus

This gallery contains 3 photos.

Toxicology International. 2015 Jan-Apr; 22(1): 152–157. This study was done to see if the common food colors tartrazine (Yellow 5), metanil yellow (a non-permitted color often used illegally) and sunset yellow (Yellow 6) may play a part in liver disease. … Continue reading

More Galleries | Leave a comment

Corder 1995: Aspirin, salicylate, sulfite and tartrazine induced bronchoconstriction. Safe doses and case definition in epidemiological studies

This gallery contains 2 photos.

Journal of Clinical Epidemiology, 1995. Oct;48(10):1269-75 Corder estimated safe doses to use for epidemiological studies by studying reactions of patients in an allergy clinic. He said that reactions to the four compounds listed in the table are common, and may … Continue reading

More Galleries | Leave a comment

Eagle 2014: ADHD impacted by sulfotransferase (SULT1A) inhibition from artificial food colors and plant-based foods

This gallery contains 2 photos.

Physiology & Behavior, 135 (2014), 174-179. SULT1A inhibitors in foods, including natural substances and artificial food colors, have a role in ADHD that can both worsen or improve symptoms. … SULT1A inhibition can influence brain catecholamines through the intermediary of … Continue reading

More Galleries | Leave a comment

Neuman 1978: The danger of “yellow dyes” (tartrazine) to allergic subjects

This gallery contains 1 photo.

Clinical Allergy. 1978 Jan;8(1): 65-8. In an Israeli hospital, Neuman et al tested the effect of 50 mg of tartrazine (Yellow 5) on 97 patients with a variety of allergic disorders and 25 with non-allergic rhinitis.  First, all patients were … Continue reading

More Galleries | Leave a comment

New FDA Data Show High Levels of Dyes in Brand-name Foods

This gallery contains 4 photos.

Little Debbie Swiss Rolls Use Yellow, Red, and Blue Dyes to Make ‘Chocolate’ Cake Reprinted from article published by the Center for Science in the Public Interest, July 18, 2016 Little Debbie Swiss Rolls have a combined 32 milligrams of … Continue reading

More Galleries | Leave a comment

Ceserani 1978: Tartrazine and prostaglandin-system

This gallery contains 2 photos.

Prostaglandins and Medicine, 1978 Dec;1(6):499-505 The authors discuss the bronchoconstriction caused by tartrazine (Yellow 5) in people who are aspirin-sensitive, as well as its effect on the prostaglandin system of guinea pig lungs.  They found that the dye inhibits formation … Continue reading

More Galleries | Leave a comment

Lockey 1977: Hypersensitivity to tartrazine (FD&C Yellow No. 5) and other dyes and additives present in foods and pharmaceutical products

This gallery contains 1 photo.

Annals of Allergy, 1977. Mar;38(3): 206-10 In this paper, Lockey describes the battery of tests he had developed to determine sensitivity to food additives and analgesics, which he says can make symptoms of asthma and chronic urticaria (hives) worse. MedLine … Continue reading

More Galleries | Leave a comment

Abrishami 1977: Aspirin intolerance–a review

This gallery contains 1 photo.

Annals of Allergy 1977 Jul;39(1):28-37 This is an early review of the combination of asthma, nasal pathology and intolerance to aspirin as a “unique syndrome”  with a tendency for diabetes as well as a prolongation of bleeding time. Abrishami mentions … Continue reading

More Galleries | Leave a comment

Stenius 1976: Hypersensitivity to acetylsalicylic acid (ASA) and tartrazine in patients with asthma

This gallery contains 2 photos.

Clinical Allergy. 1976 Mar;6(2): 119-29. In this study, Stenius and Lemola used far less of tartrazine (Yellow 5) and aspirin than what a person may normally ingest, and had to overcome chronic medication as well (see NOTES below). Nevertheless, they … Continue reading

More Galleries | Leave a comment

Settipane 1975: Aspirin intolerance. III. Subtypes, familial occurence, and cross-reactivity with tartarazine

This gallery contains 3 photos.

Journal of Allergy and Clinical Immunology, 1975. Sep;56(3): 215-21 The authors presented their evidence that in aspirin intolerance there are two mechanisma – one causing bronchospasm (breathing difficulty such as in asthma) and the other causing urticaria (hives). They also … Continue reading

More Galleries | Leave a comment

Vojdani 2015: Immune reactivity to food coloring

This gallery contains 1 photo.

Alternative Therapies in Health and Medicine, 2015. 21 Suppl 1:52-62. During the past 50 years, the amount of synthetic dye used in foods has increased by 500%.  At the same time, there has been an alarming rise in behavioral problems … Continue reading

More Galleries | Leave a comment

Batada 2016: Prevalence of Artificial Food Colors in Grocery Store Products Marketed to Children

This gallery contains 1 photo.

Clinical Pediatrics, 2016 Oct; 55(12): 1113-1119. In this study, 810 products commonly marketed to children and found in a local grocery store were evaluated.  43.2% of them contained artificial food colors (AFC), mostly Red 40, Blue 1, Yellow 5, and … Continue reading

More Galleries | Leave a comment

Malakar 2014: Minding the greens – Role of dietary salicylates in common behavioural health conditions

This gallery contains 1 photo.

Acta Alimentaria, 43(2), 344-359. QUOTE:  “Given that it is now well-known that autistic patients tend to be PST-deficient, causal link between a low-salicylate diet and the mitigation of symptom-severity seems a rather plausible hypothesis.” QUOTE:  “It is quite apparent from … Continue reading

More Galleries | Leave a comment

Stevens 2014: Amounts of artificial food dyes and added sugars in foods and sweets commonly consumed by children

This gallery contains 1 photo.

Clinical Pediatrics, 2015 Apr;54(4):309-21, e-published April 24, 2014 Numerous foods and candies were purchased from local stores and processed to measure the amount of food dyes actually in them. Several comprehensive tables provide the details, but below is a sample: Some … Continue reading

More Galleries | Leave a comment

Stevens 2014: Amounts of artificial food colors in commonly consumed beverages and potential behavioral implications for consumption in children

This gallery contains 1 photo.

Clinical Pediatrics, 2014. Feb; 53(2): 133-40. The amount of food dyes certified over the years has increased more than 5-fold since 1950 (12 mg/capita/day) to 2012 (68 mg/capita/day).  Studies that used 50 mg or more of food dyes showed a … Continue reading

More Galleries | Leave a comment

Stevenson 2014: Research review: the role of diet in the treatment of attention-deficit/hyperactivity disorder–an appraisal of the evidence on efficacy and recommendations on the design of future studies.

This gallery contains 1 photo.

Journal of Child Psychology & Psychiatry, 2014 May;55(5):416-27. The author compares 3 kinds of studies for treatment of ADHD – restricted elimination diets (RED), artificial food colour elimination (AFCE), and essential fatty acid (e.g. fish oil) supplements (SFFA).  He concludes … Continue reading

More Galleries | Leave a comment

Verlaet 2014: Nutrition, immunological mechanisms and dietary immunomodulation in ADHD.

This gallery contains 1 photo.

European Child & Adolescent Psychiatry, 2014 Jul;23(7):519-29. Verlaet discusses the common causes of GI problems, asthma, eczema, ear infections, and ADHD – involving both genes, immunity, and inflammation.  An immune imbalance can be related to food provoking ADHD-like behavior.  Food … Continue reading

More Galleries | Leave a comment