Miller 2022: Potential impacts of synthetic food dyes on activity and attention in children: A review of the human and animal evidence

Environmental Health, 2022 Apr 29;21(1):45.

Concern that synthetic food dyes may impact behavior in children prompted the California Office of Environmental Health Hazard Assessment (OEHHA) to review the research on both children and animals. 

64% of the 25 challenge studies reviewed identified evidence of a positive association, and in 52@ this association was statistically significant.  Thus, they concluded that these studies support a relationship between food dye exposure and adverse behavioral outcomes in children. 

QUOTE:  “Together, the human clinical trials and animal toxicology literature support an association between synthetic food dyes and behavioral impacts in children.”

The authors conclude, also, that there is a need to re-evaluate the current acceptable daily intakes (ADI) amounts which are based on older studies that did not consider behavioral effects.

NOTE:  I sent a collection of studies on food dyes and behavior to the OEHHA to help them in their investigation.  I have added a cover page and posted this collection as a “book” on this blog.  See it here: 

MedLine || Full Text

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