Patel 2022: The safety of pediatric use of paracetamol (acetaminopohen): A narrative review of direct and indirect evidence

Minerva Pediatrics, 2022. July 13 DOI: 10.23736/S2724-52765.22.06932-4

Use of Tylenol (paracetamol or acetaminophen) during pregnancy and early childhood has been considered safe since the 1970s.  Parents are urged to use it routinely after vaccination to prevent or control fever.

It is now known that this assumption of safety was based on “a complete absence of knowledge regarding the impact of the drug on brain development.”

At least 14 studies now show that prenatal exposure to Tylenol is associated with neurodevelopment problems, causing a statistically significant risk of developmental delays and ADHD.  Its relationship to autism is not as clear, but based on data from animal studies and several otherwise unexplained correlations, the following conclusion can be drawn:

CONCLUSION:  ” it can be concluded without any reasonable doubt that oxidative stress puts some babies and children at risk of paracetamol-induced neurodevelopmental injury, and that postnatal exposure to paracetamol in those susceptible babies and children is responsible for many if not most cases of ASD.”

 MedLine  ||  Full Text

This entry was posted in 2021-2025, Autism, Brain, Prenatal Exposure, Vaccination & Immunity. Bookmark the permalink.

Leave a Reply

Your email address will not be published. Required fields are marked *