Shaywitz 1979: Effects of chronic administration of food colorings on activity levels and cognitive performance in developing rat pups treated with 6-hydroxydopamine

rats runningNeurobehavioral Toxicology, 1979.  Spring;1(1):41-7.  (Today called Neurotoxicology and Teratology)

In a study on rat pups, the highest dose of food dyes caused the greatest activity.  Even after a half hour, the pups only calmed down by 7.25% — while the normal pups had calmed down by more than 30%.

NOTE:   2.0 mg/kg is about the same as 60 mg food dye for a 30 kg (66 pound) child.  60 mg is about what you get in a single red-frosted cupcake. 

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