Al-Shabib 2019: Allura Red Rapidly Induces Amyloid-Like Fibril Formation in Hen Egg White Lysozyme at Physiological pH

International Journal of Biological Macromolecules. 127: 297-305

Red 40, with hen egg white lysozyme (HEWL), forms amyloid-like aggregates. (A lysozyme is an enzyme in human tears and egg white.)

The amyloid fibril formation can be observed by an electron microscope, is very quickly formed, and needs very little Red 40.

NOTE:  Amyloid fibrils are involved with most neurodegenerative disorders such as Alzheimer’s and Parkinson’s.

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