Gundry 2021: mRNA COVID Vaccines Dramatically Increase Endothelial Inflammatory Markers and ACS Risk as Measured by the PULS Cardiac Test: a Warning?

Circulation, Vol 144, Issue Suppl_1

For about 8 years, Dr. Steven Gundry had been monitoring a group of 566 patients  with a PULS (Protein Unstable Lesion Signature) test, and they averaged an 11% risk of having an acute coronary event, such as a heart attack, within 5 years.  (After all, these were his patients and he is a cardiologist, so we can expect their risk to be elevated).   

When Dr. Gundry tested these patients again after they had taken the Covid-19 vaccine, he found their average risk had more than doubled to 25%.

Dr. Mercola’s November article about these findings can be found here.     For your convenience, I will paste below his “Story at a Glance.”


Using the PULS cardiac test, researchers have found Pfizer and Moderna mRNA COVID shots dramatically increase biomarkers associated with thrombosis, cardiomyopathy and other vascular events following vaccination

Pre- and post-injection PULS tests for 566 patients were compared.  On average, their PULS scores went from an 11% five-year risk for acute coronary syndrome, to a more than double, 25%, five-year risk

Those who got the injection for fear that COVID-19 might adversely affect their heart now face the grim reality that they’ve exchanged a potential risk for a more certain one

Another paper details how the mRNA shot can cause thrombocytopenia (low platelet count) through a mechanism that involves the activation of platelets by antibodies against the spike protein (anti-spike antibodies)

A mystery that remains to be solved is why only certain people with antibodies to the spike protein (anti-spike antibodies) go on to develop symptoms of platelet activation and thrombocytopenia. One hypothesis is that only a subset of the anti-spike antibodies formed after vaccination can activate platelets and cause thrombocytopenia

Dr. Gundry concluded:  “the mRNA vacs dramatically increase inflammation on the endothelium and T-cell infiltration of cardiac muscle and may account for the observations of increased thrombosis, cardiomyopathy, and other vascular events following vaccination.”

Abstract  || Dr. Mercola’s article on this subject

Related papers referred to by Dr. Mercola in his paper above: 

NOTE:  There is an “expression of concern” on Dr. Gundry’s abstract.  I tracked it down, and it seems to be a complaint that the abstract contains typographical errors and uses anecdotal information.  It is true that there is one typo, as PULS is spelled “PLUS” when first introduced, but I have seen far worse in published papers.  Later, the author wrote “pts” for “patients” but the intent is certainly clear.  There are no other typos.  I cannot imagine why testing a group of patients before an intervention (the vaccine) and again afterwards would be called “anecdotal.”  While it is not a double-blind study, it is certainly a valid design, called quasi-experimental or trend analysis.  My best guess is that somebody didn’t like the results — which are admittedly horrific — and is trying to downgrade the study.

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