By studying the brains of mice whose mothers were exposed to titanium dioxide (TiO2) nanoparticles during pregnancy, the researchers determined changes in gene expression affecting several parts of the brains of the mice, resulting in problems that showed up as they developed.
QUOTE: ” The analysis provides data to support the hypothesis that maternal TiO2 exposure results in alteration to the cerebral cortex, olfactory bulb and the regions intimately related to dopamine systems of offspring mice.”
- Shimizu 2009: Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse
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- Takeda 2009: Nanoparticles transferred from pregnant mice to their offspring can damage the genital and cranial nerve systems.