Category Archives: Year of Publication

Gray 2013: Salicylate elimination diets in children: Is food restriction supported by the evidence?

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The Medical Journal of Australia, 2013. Jun 17; 198(11): 600-2. Gray was treating patients who had tried the low-salicylate diet (called the FAILSAFE diet) used in Australia, which is more restrictive than the Feingold diet, eliminating both more of the … Continue reading

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Husarova 2013: Monosodium glutamate toxic effects and their implications for human intake: A review

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JMED Research, Vol. 2013 (2013) This is a review of the studies about MSG and its influence on different systems in humans.  Effects of injected MSG into rats included neuron damage, and prefrontal cerebral cortex changes, but such tests cannot … Continue reading

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Sonuga-Barke 2013: Nonpharmacological Interventions for ADHD: Systematic Review and Meta-Analyses of Randomized Controlled Trials of Dietary and Psychological Treatments

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American Journal of Psychiatry, 2013.  March. 170(3): 275-89. This paper is a review of dietary and psychological treatments for ADHD. QUOTE (Conclusion):  “Free fatty acid supplementation and artificial food color exclusions appear to have beneficial effects on ADHD symptoms, although … Continue reading

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Stevens 2013: Mechanisms of behavioral, atopic, and other reactions to artificial food colors in children

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Nutrition Review, 2013 May;71(5):268-81. Stevens reviews the research on mechanisms by which food dyes and common foods may cause behavioral changes in children with and without ADHD.  The three potential mechanisms are toxicological, antinutritional, and hypersensitivity. Suggestions for future studies … Continue reading

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Artificial sweeteners are worse than we thought

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We already know too much sugar is bad for you ………but ARTIFICIAL sugar is worse. Click on the picture to see a short but important video from an article in TIME, May 20, 2016. Related studies:  (Get password) Azad 2016 … Continue reading

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Whiteley 2013: Gluten- and casein-free dietary intervention for autism spectrum conditions

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Frontiers in Human Neuroscience, 2013 Jan 4;6:344. This is a review of evidence suggesting that a gluten-free diet, a casein-free diet (or both) are helpful for people on the autism spectrum. QUOTE:   “Although not wholly affirmative, the majority of published … Continue reading

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Arnold 2012: Artificial food colors and attention-deficit/hyperactivity symptoms: Conclusions to dye for

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Neurotherapeutics. 2012 Jul;9(3):599-609. Arnold reviews the history of the effects of artificial food colors (AFC) on ADHD and the testimony to the 2011 FDA Food Advisory Committee. Arnold discusses possible biological mechanisms such as the effects of food dyes on … Continue reading

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Millichap 2012: The diet factor in attention-deficit/hyperactivity disorder

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Pediatrics, 2012 Feb;129(2): 330-7. Millichap says his article is a comprehensive overview of the role of diet for treatment of children with ADHD “when pharmacotherapy has proven unsatisfactory or unacceptable.”  He promises to talk about new research. Unfortunately, he falls … Continue reading

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Saab 2012: The effect of diet supplementation on children with ADHD

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Lebanese American University, Masters Thesis 2012 In a project for her Masters Degree in Education, Linda Saab performed a case study on a 9 year old boy in Beirut who was diagnosed with ADHD.   Although he was observed for 5 … Continue reading

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Weiss 2012: Synthetic Food Colors and Neurobehavioral Hazards: The View from Environmental Health Research

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Environmental Health Perspectives, 2012 Jan;120(1):1-5. Dr. Weiss examines the basis of the FDA’s position on food dyes, the decision of the Food Advisory Committee, and the reasons that this is an environmental health issue He points out that they limited … Continue reading

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Hoekstra 2011: Is there potential for the treatment of children with ADHD beyond psychostimulants?

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European Child & Adolescent Psychiatry, 2011. 20 (9), 431-2. Concerned about the enormous increase in use of psychostimulant drugs such as Ritalin, the authors of this editorial discuss the research supporting the use of other options.  In particular, they find … Continue reading

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Kamel 2011: The Potential Health Hazard of Tartrazine and Levels of Hyperactivity, Anxiety-Like Symptoms, Depression and Anti-social behaviour in Rats

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Journal of American Science, 2011; 7 (6): 1211-1218. This paper from Egypt describes a double-blind controlled study on rats to determine the behavioral effects of long-term exposure to various doses of tartrazine (E102, Yellow 5) provided in the drinking water … Continue reading

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Pelsser 2011: Effects of a restricted elimination diet on the behaviour of children with attention-deficit hyperactivity disorder (INCA study): a randomised controlled trial

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The Lancet, 2011. Feb 5;377 (9764): 494-503 This is a study of 100 children diagnosed with ADHD but not selected on any basis of expectation of a dietary effect.   The children were randomly assigned to an experimental diet group and … Continue reading

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Stevens 2011: Dietary sensitivities and ADHD symptoms: thirty-five years of research

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Clinical Pediatrics (Phila), 2011. Apr; 50(4): 279-93. In their review of the literature, Stevens et al conclude that the evidence indicates that a diet free of food dyes is appropriate for “children who have not responded satisfactorily to conventional treatment, … Continue reading

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Pelsser 2010: Effects of food on physical and sleep complaints in children with ADHD: a randomised controlled pilot study

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European Journal of Pediatrics, 2010 Sep;169(9): 1129-38. The 27 children in the Pelsser 2009 study were also evaluated for the effect of their diet condition on their sleep problems and other physical complaints.  Such complaints included headaches, bellyaches, unusual thirst, … Continue reading

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Stevenson 2010: The Role of Histamine Degradation Gene Polymorphisms in Moderating the Effects of Food Additives on Children’s ADHD Symptoms

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American Journal of Psychiatry. 2010 Sep;167(9): 1108-15 Stevenson analyzed the reactions of children in the McCann (2007) study to see why not all children react to additives in the same way.  He found that variation in several genes that control … Continue reading

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Pelsser 2009: A randomised controlled trial into the effects of food on ADHD

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European Child & Adolescent Psychiatry. 2009 Jan;18(1):12-9. In a randomized controlled trial in the Netherlands, 27 children were assigned either to an elimination diet or to a “waiting list” control group for 5 weeks, beginning after a 2-week “baseline” diet … Continue reading

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Curtis 2008 Nutritional and environmental approaches to preventing and treating autism and attention deficit hyperactivity disorder (ADHD): a review

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Journal of Alternative and Complementary Medicine, 2008.  Jan-Feb; 14(1): 79-85. This is a review of literature available in 2008. The authors say many of the studies link exposure to toxins such as mercury, lead, and pesticides, as well as prenatal … Continue reading

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Prescrire International 2009: Artificial food colouring and hyperactivity symptoms in children

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Prescrire International, 2009. Oct; 18(103): 215 (no author listed) In a health assessment of artificial food dyes, Prescrire International, a non-profit organization providing information and continuing education for healthcare professionals, considers the hypothesis that artificial food dyes worsen hyperactivity symptoms … Continue reading

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McCann 2007: Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial

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Lancet, September 6, 2007 As a followup to the earlier Bateman (2004) study, the authors retested 153  toddlers as well as 144 elementary school (8/9 years old) children from the general population.   They were briefly put on a dye-free … Continue reading

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Husain 2006: Estimates of dietary exposure of children to artificial food colours in Kuwait

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Food Additives & Contaminants, 2006. Mar; 23(3): 245-51. Husain evaluated the amount of food dyes consumed by children in 58 schools in Kuwait, and found that the amounts of four of the colors were 4 to 8 times above the … Continue reading

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Inomata 2006: Multiple chemical sensitivities following intolerance to azo dye in sweets in a 5-year-old girl

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Allergology International, 2006. Jun; 55(2):203-5. This is a case report about a 5-year-old girl in Japan with multiple recurrent problems:  urticaria (hives), angioedema (swelling), headaches, dyspnea (shortness of breath), loss of consciousness, and abdominal pain.  Her symptoms were made worse … Continue reading

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Lau 2006: Synergistic Interactions Between Commonly Used Food Additives in a Developmental Neurotoxicity Test

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Toxicological Sciences. 2006 Mar; 90(1):178-87. This is one of the few studies examining and comparing the neurotoxic activity of food additives alone and in combination.   After determining how much of each additive reduces neurite development by 20%, Lau combined pairs … Continue reading

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Lien 2006: Consumption of soft drinks and hyperactivity, mental distress, and conduct problems among adolescents in Oslo, Norway

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American Journal of Public Health, 2006. Oct;96(10):1815-20 The authors surveyed almost 5,500 students in 10th grade to see how many sugar-containing soft drinks they consumed per day and to assess their mental health and conduct. AUTHORS’ CONCLUSIONS:  “High consumption levels … Continue reading

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Niederhofer 2006: A preliminary investigation of ADHD symptoms in persons with celiac disease

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Journal of Attention Disorders, 2006. Nov;10(2):200-4. Because several studies had reported a possible association of celiac disease (CD) and ADHD symptoms, the authors evaluated 132 participants diagnosed with CD – both children and adults – for ADHD symptoms before they … Continue reading

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Bateman 2004: The effects of a double blind, placebo controlled, artificial food colourings and benzoate preservative challenge on hyperactivity in a general population sample of preschool children

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Archives of Disease in Childhood. 2004 Jun;89(6):506-11. The authors put 277  3-year-old children from the general population on a diet without artificial food dyes or benzoate preservatives for a week, and then challenged them at various times with a drink … Continue reading

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Schab 2004: Do artificial food colors promote hyperactivity in children with hyperactive syndromes? A meta-analysis of double-blind placebo-controlled trials

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Journal of Developmental and Behavioral Pediatrics, 2004 Dec;25(6):423-34. Searching 10 databases for double-blind placebo-controlled trials on the effects of artificial food dyes, Schab and Trinh found 15 that met their criteria. QUOTE:  “Our meta-analysis supports the hypothesis that AFCs (artificial … Continue reading

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Dengate 2002: Controlled trial of cumulative behavioural effects of a common bread preservative

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Journal of Paediatrics and Child Health, 2002. Aug;38(4):373-6 In Australia, 27 children whose behavior had improved on the Royal Prince Alfred Hospital diet were enrolled in a double-blind placebo-controlled test of the bread preservative calcium propionate (preservative code 282).  More … Continue reading

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Pelsser 2002: Favourable effect of a standard elimination diet on the behavior of young children with attention deficit hyperactivity disorder (ADHD): a pilot study

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Nederlandsch tijdschrift voor geneeskunde 2002, Dec 28;146(52):2543-7. 36 boys and 4 girls, diagnosed with ADHD, were put on an oligoantigenic (few foods – rice, turkey, pear and lettuce) diet for two weeks.  9 children (23%) withdrew from the study because of … Continue reading

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Bennett 1998 The Shipley Project: Treating Food Allergy to Prevent Criminal Behaviour in Community Settings

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Journal of Nutritional & Environmental Medicine , Vol.8, No.1, Mar.1998, pp.77-83 All 9 children with disruptive and/or criminal behavior in this study were found to have a number of food allergies or intolerances and mineral imbalances, particularly zinc. Three also … Continue reading

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Starobrat-Hermelin 1998:   The effect of deficiency of selected bioelements on hyperactivity in children with certain specified mental disorders

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Annales Academiae Medicae Stetinensis, 1998;44:297-314 Deficiencies of magnesium, copper, zinc, calcium, and iron occur more in children with ADHD, and magnesium deficiency is the most frequent.   Starobrat-Hermelin studied a group of 110 hyperactive children who also had a variety … Continue reading

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Bennett 1997: The Health of Criminals Related to Behaviour, Food, Allergy and Nutrition: A Controlled Study of 100 Persistent Young Offenders

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Journal of Nutritional & Environmental Medicine, Vol.7, No.4 Dec 1997 pp.359-366 About 75% of persistent young offenders have behaviors linked to food sensitivity and nutrition problems; only 18% of young non-offenders have such problems. MedLine || Full Text || Get Password

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Schmidt 1997: Does oligoantigenic diet influence hyperactive/conduct-disordered children–a controlled trial

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European Child & Adolescent Psychiatry, 1997. Jun;6(2):88-95. Fig. 1 Study design Schmidt compared the effectiveness of an oligoantigenic (few foods) diet with Ritalin for hyperactive disruptive children (today called conduct disorder).   44% responded to Ritalin while 24% responded equally well … Continue reading

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Uhlig 1997: Topographic mapping of brain electrical activity in children with food-induced attention deficit hyperkinetic disorder

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European Journal of Pediatrics, 1997. Jul;156(7):557-61. Uhlig carried out EEG brain mapping on 15 children with food-induced ADHD, both when they were on their diet and when they had been given provoking foods. Consuming the provoking foods caused a significant … Continue reading

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Reyes 1996: Effect of organic synthetic food colours on mitochondrial respiration

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Food Additives and Contaminants, 1996. Jan;13(1):5-11 In this lab study, 11 artificial food dyes – not all of them used in the US — were tested to determine their effect on the mitochondria of rat liver and kidney. NOTE:  Mitochondria … Continue reading

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Boris 1994: Foods and Additives are Common Causes of the Attention Deficit Hyperactive Disorder in Children

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Annals of Allergy, May 1994, Vol. 72, pp. 462-8. 73% of 26 children with ADHD responded favorably to a diet eliminating reactive foods and artificial colors. 16 of the improved children were given a double blind challenge with 100 mg … Continue reading

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Rowe 1994: Synthetic Food Coloring and Behavior: A Dose Response Effect in a Double-Blind, Placebo-Controlled, Repeated-Measures Study

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Journal of Pediatrics, November 1994, Vol. 135, pp.691-8 150 of 200 children [75%] improved on an open trial of a diet free of synthetic food coloring, and deteriorated upon introduction of foods containing synthetic colorings. 34 other “clear” or “suspected” … Continue reading

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Carter 1993: Effects of a Few Foods Diet in Attention Deficit Disorder

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Archives of Disease in Childhood, November 1993, Vol. 69 (5), pp.564-8 59 of 78 children (75.6%) referred for “hyperactive behavior” improved on an open trial of an elimination diet.  19 of them were studied in a placebo-controlled double-blind challenge protocol. … Continue reading

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Egger 1992: Effect of diet treatment on enuresis in children with migraine or hyperkinetic behavior

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Clinical Pediatrics (Phila) 1992 May;31(5):302-7. 21 children with migraine and/or hyperkinetic behavior disorder also had daytime or nighttime enuresis (wetting).  Use of an oligoantigenic (few-foods) diet controlled their migraine and/or hyperkinesis, and for 76% of them the diet also stopped … Continue reading

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Novembre 1992: Unusual reactions to food additives

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Pediatria Medica e Chirurgica 1992 Jan-Feb;14(1):39-42 The author describes two cases of reactions to the food additives tartrazine (Yellow 5) and benzoates involving mainly the central nervous system (headache, migraine, overactivity, concentration and learning difficulties, depression) and joints (arthralgias), confirmed … Continue reading

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Schoenthaler 1991: Applied Nutrition and Behavior

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Journal of Applied Nutrition, November 1, 1991, Vol. 43. In a review of diet changes made in 813 prisons in California, implementation of “nutrient dense diets” resulted in “significantly improved conduct, intelligence, and/or academic performance” Full Text || Get Password

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Pollock 1990: Effect of artificial food colours on childhood behaviour

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Archives of Disease in Childhood, 1990.  Jan;65(1):74-7, Heart and Lung Institute, Brompton Hospital, London. Pollock did a double-blind placebo-controlled challenge study on 19 children who had improved previously on an additive-free diet.   He didn’t use any additives but food dyes, … Continue reading

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Sarantinos 1990: Synthetic Food Colouring and Behavioural Change in Children with Attention Deficit Disorder: A Double-Blind, Placebo Controlled, Repeated Measures Study

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Proceedings of the Nutrition Society of Australia, 1990 pg. 233. Sarantinos studied 13 children,  4-14 years old, who had been at least 6 weeks on a diet free of synthetic food dyes as part of their treatment for ADHD.  The … Continue reading

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Ward 1990: The influence of the chemical additive tartrazine on the zinc status of hyperactive children: A double-blind placebo-controlled study

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Journal of Nutritional Medicine; 1 (1). 1990. 51-58. Ward first studied the zinc status in various tissues (blood, hair, saliva, etc) in 20 hyperactive boys compared to 20 non-hyperactive boys.  Then, in a double-blind placebo-controlled study of 10 hyperactive boys … Continue reading

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Egger 1989: Oligoantigenic diet treatment of children with epilepsy and migraine

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Journal of Pediatrics, 1989. Jan;114(1):51-8. Egger put 45 children with epilepsy and recurrent headaches, abdominal symptoms, or hyperactivity on an oligoantigenic (few foods) diet.   36 of them — 80% — improved. QUOTE:  “Headaches, abdominal pains, and hyperkinetic behavior ceased … Continue reading

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Kaplan 1989: Overall Nutrient Intake of Preschool Hyperactive and Normal Boys

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Journal of Abnormal Child Psychology, April 1989, Vol. 17(2), pp.127-32. Kaplan compared food diaries of children with and without ADHD and concluded that it was idiosyncratic sensitivities to components in the diet rather than a different overall diet. MedLine || … Continue reading

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Rowe 1988: Synthetic Food Colourings and “Hyperactivity”: a Double-Blind Crossover Study

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Australian Paediatric Journal, April 1988, Vol. 24 (2), pp. 143-7 Of 220 children referred for suspected hyperactivity, 55 were put on a 6-week trial of the Feingold Diet.    40 of them — 72.7% — exhibited improved behavior, and 26 of … Continue reading

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Burlton-Bennett 1987: A Single Subject Evaluation of the K-P Diet for Hyperkinesis

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Journal of Learning Disabilities, 1987 Jun-Jul;20(6):331-5, 346. A single subject ABAB (on-off-on-off) design was used to test the effectiveness of the Feingold (K-P) diet in the treatment of a 6-year-old hyperkinetic male who seemed to  be diet-responsive.  His behavior was … Continue reading

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David 1987: Reactions to dietary tartrazine

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Archives of Disease in Childhood, 1987. Feb;62(2):119-22. In a double-blind study, David challenged 24 of his patients who had been using diet for ADHD with benzoic acid (a preservative) and a large dose of coloring — 250 mg of Yellow … Continue reading

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Gross 1987: The effect of diets rich in and free from additives on the behavior of children with hyperkinetic and learning disorders

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Journal of the American Academy of Child and Adolescent Psychiatry. 1987. Jan;26(1):53-5. Gross carried out a diet study in a summer camp which is a great way to totally control the diet and get solid results in a study. NOTE:  … Continue reading

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Schoenthaler 1986: The Impact of a Low Food Additive and Sucrose Diet on Academic Performance in 803 New York City Public Schools

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International Journal for Biosocial Research, 1986, 8(2); 185-195. Over 4 years, 803 New York City schools changed their breakfast and lunch programs.  They lowered sucrose, synthetic food color/flavors, and two preservatives (BHA and BHT). For each change, there was an … Continue reading

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Egger 1985: Controlled Trial of Oligoantigenic Treatment in the Hyperkinetic Syndrome

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The Lancet, 9;1(8428):540-5. 62 of 76  (81.6%) overactive children improved by at least one grade level on an oligoantigenic (few foods) diet.  Benzoic acid and tartrazine (Yellow 5) were the most common problems, but all children had other sensitivities as … Continue reading

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Menzies 1984: Disturbed children: the role of food and chemical sensitivities

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Nutrition and Health. 1984; 3(1-2): 39-54. Menzies reviews the existing literature and presents a number of case studies of children with idiosyncratic responses to foods and additives. QUOTE:  “Perhaps not enough attention has been paid to the role of biological … Continue reading

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Egger 1983: Is migraine food allergy? A double-blind controlled trial of oligoantigenic diet treatment

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Lancet, 1983. Oct 15;2(8355):865-9 93% of 88 children with severe frequent migraine recovered on an oligoantigenic (few foods) diet.  40 of them were challenged with various foods in a double-blind test, establishing that it was the diet that had helped.  … Continue reading

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Mattes 1983: The Feingold diet: a current reappraisal

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Journal of Learning Disabilities, 1983.  Jun-Jul;16(6):319-23. Mattes gives his opinion that improvement on the Feingold diet is  “based on anecdotal evidence;” he claims that the studies show the diet “is probably not effective, except perhaps in a very small percentage … Continue reading

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Feingold 1982: The role of diet in behaviour

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Ecology of Disease, 1982. 1(2-3):153-65 QUOTE:   The increase in behavioural disorders accompanied by a persistent drop in scholastic performance coupled with the continuing rise in the prevalence of delinquency is undoubtedly one of the most important expressions of the disruption … Continue reading

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Goldenring 1982: Sulfanilic acid: behavioral change related to azo food dyes in developing rats

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Neurobehavioral Toxicology and Teratology, 1982. Jan-Feb;4(1): 43-9. Goldenring studied the effects of giving sulfanilic acid to rat pups.  He chose this chemical because it is formed when azo food dyes are digested.  He gave the sulfanilic acid to normal rat … Continue reading

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Salamy 1982: Physiological changes in hyperactive children following the ingestion of food additives

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International Journal of Neuroscience, 1982. May;16(3-4):241-246 QUOTE:  “… The physiological measures [EEG and heart rate] were obtained prior to and following the ingestion of drinks containing food additives or placebos, which were administered in a double-blind, randomized, crossover procedure. … … Continue reading

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Mattes 1981: Effects of artificial food colorings in children with hyperactive symptoms. A critical review and results of a controlled study

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Archives of General Psychiatry. 1981. June; 38(6): 714-8 Mattes claimed he tried to maximize the behavioral effects of artificial food dyes by (1) studying only children already on the Feingold diet,  (2) trying to exclude placebo responders, and (3) administering … Continue reading

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Swanson 1980: Food Dyes Impair Performance of Hyperactive Children on a Laboratory Learning Test

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Science, March 28, 1980, Vol. 207. pp.1485-7 QUOTE:  “The performance of the hyperactive children on paired-associate learning tests on the day they received the dye blend was impaired relative to their performance after they received the placebo, but the performance … Continue reading

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